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Toshihiko Hibino Selected Research

bleomycin hydrolase

5/2021Seasonal variability of epidermal Bleomycin Hydrolase activity in healthy children and pediatric patients with atopic dermatitis.
3/2011Bleomycin hydrolase is regulated biphasically in a differentiation- and cytokine-dependent manner: relevance to atopic dermatitis.

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Toshihiko Hibino Research Topics

Disease

8Neoplasms (Cancer)
01/2019 - 07/2002
7Neoplasm Metastasis (Metastasis)
01/2019 - 01/2013
6Inflammation (Inflammations)
04/2018 - 02/2010
5Atopic Dermatitis (Atopic Eczema)
05/2021 - 02/2011
5Melanoma (Melanoma, Malignant)
01/2019 - 01/2013
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2020 - 01/2002
3Psoriasis (Pustulosis Palmaris et Plantaris)
08/2018 - 01/2002
2Parakeratosis
02/2011 - 02/2010
2Alopecia (Baldness)
06/2004 - 06/2003
1Rheumatoid Arthritis
03/2020
1Thymoma (Thymic Carcinoma)
01/2020
1Breast Neoplasms (Breast Cancer)
01/2019
1Lung Neoplasms (Lung Cancer)
01/2019
1Skin Diseases (Skin Disease)
05/2008

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
01/2020 - 07/2002
4CytokinesIBA
01/2019 - 05/2008
3LigandsIBA
01/2019 - 01/2013
3CD146 AntigenIBA
01/2019 - 04/2018
2bleomycin hydrolaseIBA
05/2021 - 03/2011
2TNF Receptor-Associated Factor 2 (TRAF2)IBA
01/2019 - 11/2016
2Transcription Factors (Transcription Factor)IBA
01/2019 - 01/2019
2Cell Surface ReceptorsIBA
01/2019 - 01/2016
2Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA
04/2018 - 01/2016
2Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
04/2018 - 01/2013
2Metalloproteases (Metalloproteinases)IBA
11/2016 - 01/2013
2Caspase 14IBA
01/2014 - 02/2011
2Filaggrin ProteinsIBA
03/2013 - 03/2011
2Peptide Hydrolases (Proteases)FDA Link
03/2013 - 07/2002
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2008 - 07/2002
2CaspasesIBA
06/2004 - 06/2003
2AntigensIBA
07/2002 - 01/2002
2squamous cell carcinoma-related antigenIBA
07/2002 - 01/2002
2SerpinsIBA
07/2002 - 01/2002
1Biosimilar PharmaceuticalsIBA
03/2020
1Etanercept (Enbrel)FDA Link
03/2020
1trichohyalinIBA
01/2020
1MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA
01/2019
1Biological ProductsIBA
01/2019
1Monoclonal AntibodiesIBA
01/2019
1Fc Receptors (Fc Receptor)IBA
01/2019
1Neutralizing AntibodiesIBA
01/2019
1matrix metalloproteinase 25IBA
01/2019
1NucleotidesIBA
08/2018
1InflammasomesIBA
08/2018
1Cell Adhesion MoleculesIBA
01/2016
1Heparitin Sulfate (Heparan Sulfate)IBA
01/2016
1Receptor for Advanced Glycation End ProductsIBA
08/2014
1Leukocyte L1 Antigen Complex (Calgranulin)IBA
01/2013
1Calcium-Binding ProteinsIBA
01/2013
1Matrix Metalloproteinases (MMPs)IBA
01/2013
1EnzymesIBA
02/2011
1Therapeutic UsesIBA
02/2010
1Biomarkers (Surrogate Marker)IBA
02/2010
1Interleukin-6 (Interleukin 6)IBA
05/2008
1Salicylic Acid (2 Hydroxybenzoic Acid)FDA LinkGeneric
02/2006
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
02/2006
1Testosterone (Sustanon)FDA Link
06/2004
1Cholestenone 5 alpha-Reductase (5 alpha-Reductase)IBA
06/2004
1Transforming Growth Factor beta2IBA
06/2004
1AndrogensIBA
06/2004
1Transforming Growth Factor beta (TGF-beta)IBA
06/2003
1Messenger RNA (mRNA)IBA
07/2002

Therapy/Procedure

2Therapeutics
01/2019 - 04/2018